When people hear the word "dementia" they may think of Alzheimer disease. Dementia is a slow, progressive decline in mental function in which memory, thinking, judgment, and the ability to learn are impaired.For most dementias, no treatment can restore mental function. However, treating disorders that are worsening the dementia sometimes slows mental decline. For people who have dementia and depression, antidepressants (such as sertralineSome Trade Names
ZOLOFTand paroxetineSome Trade Names PAXIL(see Drugs Used to Treat Depression) and counseling may help, at least temporarily. Abstaining from alcohol can result in long-term improvement.The use of certain drugs (such as nonsteroidal anti-inflammatory drugs [NSAIDs]) to prevent and slow the progression of Alzheimer's disease is under study. Estrogen and vitamin E may help prevent and slow progression of the disease, although study results are inconsistent. Before any of these substances are taken, their risks and benefits should be discussed with a doctor.