Ignoring the dumb semantics: Actually, in the East (I assume you're referring to buddhistic thought), the dissolution of self is what's practiced, which is the opposite of what you're saying. With the discovery of neuroplasticity, the notion of a "true self" has gone out the window. Your brain is changing all the time, and as you read this, the concept of "you" is dissolving piece by piece, to be replaced by a new "you".
And there it is, the new "you", with the adoption of the information you just gained. Now wait ten seconds for "your" brain to process it.
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Now we have an even newer "you," with the information you gained, and the information "you" gained from processing that information - regardless of whether "you" rejected or accepted it as a whole, the very processing of information changed "you".